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Falciparum Malaria Vaccines



Researchers from Ehime University, Department of Molecular report recent findings in falciparum malaria vaccines



April 16th, 2008

Investigators publish new data in the report 'Diversity and evolution of the rhoph1/clag multigene family of Plasmodium falciparum.' According to a study from Japan, "A complex of high-molecular-mass proteins (PfRhopH) of the human malaria parasite Plasmodium falciparum induces host protective immunity and therefore is a candidate for vaccine development. Understanding the level of polymorphism and the evolutionary processes is important for advancements in both vaccine design and knowledge of the evolution of cell invasion in this parasite."

"In the present study, we sequenced the entire open reading frames of seven genes encoding the proteins of the PfRhopH...


Source: Vaccine Weekly (2008-04-16)

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