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Vaccine Weekly

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Immunization



New findings from Xinjiang University in the area of immunization published



April 16th, 2008

Scientists discuss in 'Enhanced contraceptive response by co-immunization of DNA and protein vaccines encoding the mouse zona pellucida 3 with minimal oophoritis in mouse ovary' new findings in immunization. "Zona pellucida 3 (ZP3) acts as the primary sperm receptor, induces autoantibody that can prevent oocyte fertilization and has been proposed as a vaccine candidate for contraception in humans. Due to the elicited autoreactive T cell inflammation that causes ovarian destruction, ZP3-based vaccine with removed T epitopes from the ZP3 is considered as a preferred approach," researchers in Urumqi, People's Republic of China report.

"We present here a new strategy to...


Source: Vaccine Weekly (2008-04-16)

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