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Vaccine Weekly

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Cancer Vaccines



New cancer vaccines research reported from Kanazawa University, Medical Department



April 16th, 2008

According to recent research published in the journal Digestion, "In the early 1990s, some prospective controlled trials revealed the superiority of chemotherapy for survival compared with best supportive care for advanced or metastatic colorectal carcinoma. Until recently, 5-fluorouracil (5-FU) and leucovorin 0) were the standard therapies against advanced or metastatic colorectal cancer."

"Theoretically, LV should increase the antitumor activity of 5-FU, although this effect of LV addition has been controversial. A meta-analysis which analyzed 21 randomized controlled trials revealed that a combination of 5-FU and LV doubled the response rate compared with 5-FU...


Source: Vaccine Weekly (2008-04-16)

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