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Burkholderia
Studies from S.P. Sivalingam and co-researchers yield new data on Burkholderia
April 16th, 2008
According to a study from Singapore, Singapore, "Melioidosis, a potentially fatal disease of humans and animals, is caused by the Gram-negative bacterium, Burkholderia pseudomallei. There is no approved vaccine or effective prophylaxis." "Given its potential as a bioterrorism agent and a cause of serious laboratory-acquired infection, we studied the efficacy of pre- and post-exposure oral antibiotic prophylaxis in BALB/c mice infected with aerosolized B. pseudomallei through the inhalational route. Amoxicillin/clavulanic acid, doxycycline or co-trimoxazole was administered 48 h before infection as pre- exposure prophylaxis, orally, twice daily and continued up to 10...
Source: Vaccine Weekly (2008-04-16)
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