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Vaccine Weekly

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Malaria Vaccines



Reports outline malaria vaccines research from University Federal of Minas Gerais



April 16th, 2008

Researchers detail in 'Direct effect of Plasmodium vivax recombinant vaccine candidates AMA-1 and MSP-119 on the innate immune response,' new data in malaria. According to a study from Brazil, "The recombinant apical membrane antigen 1 (AMA-1) and 19-kDa fragment of merozoite surface protein (MSP-1(19)) are the lead candidates for inclusion in a vaccine against blood stages of malaria due to encouraging protective studies in humans and animals. Despite the importance of an efficacious malaria vaccine, vaccine-related research has focused on identifying antigens that result in protective immunity rather than determining the nature of anti-malarial immune effector mechanisms."

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Source: Vaccine Weekly (2008-04-16)

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