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HIV/AIDS
Scientists at University of Washington report research in HIV/AIDS
April 16th, 2008
According to a study from the United States, "Consider a placebo-controlled preventive HIV vaccine efficacy trial. An HIV amino acid sequence is measured from each volunteer who acquires HIV, and these sequences are aligned together with the reference HIV sequence represented in the vaccine." "We develop genome scanning methods to identify positions at which the amino acids in infected vaccine recipient sequences either (A) are more divergent from the reference amino acid than the amino acids in infected placebo recipient sequences or (13) have a different frequency distribution than the placebo sequences, irrespective of a reference amino acid. We consider t-test-type...
Source: Vaccine Weekly (2008-04-16)
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