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Obesity and Diabetes Vaccines
New findings from Walter and Eliza Hall Institute of Medical Research in the area of obesity and diabetes vaccines described
April 23rd, 2008
Research findings, 'Vaccination against self to prevent autoimmune disease: the type 1 diabetes model,' are discussed in a new report. "Immune tolerance to self-antigens is physiological. Given a repertoire of self-reactive, potentially pathogenic lymphocytes, therapeutic options to diminish autoimmune disease risk include deletion, reduced activation or increased regulation of self-reactive lymphocytes by means that mimic or promote physiological mechanisms of immunity," investigators in Parkville, Australia report. "Vaccination with self-antigen to promote self-antigen-specific tolerance, 'negative vaccination', may represent the most specific and potentially safest...
Source: Vaccine Weekly (2008-04-23)
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