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Vaccines
Investigators at University of Wollongong have published new data on vaccines
April 23rd, 2008
Data detailed in 'Opacity factor activity and epithelial cell binding by the serum opacity factor protein of Streptococcus pyogenes are functionally discrete' have been presented. "Serum opacity factor (SOF) is a unique multifunctional virulence determinant expressed at the surface of Streptococcus pyogenes and has been shown to elicit protective immunity against GAS infection in a murine challenge model. SOF consists of two distinct domains with different binding capacities: an N-terminal domain that binds apolipoprotein AI and a C-terminal repeat domain that binds fibronectin and fibrinogen," scientists writing in the Journal of Biological Chemistry report....
Source: Vaccine Weekly (2008-04-23)
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