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Vaccine Weekly

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Vaccines



Researchers from University of Wisconsin detail findings in vaccines



April 23rd, 2008

New research, 'Effects of IL-7 on memory CD8 T cell homeostasis are influenced by the timing of therapy in mice,' is the subject of a report. According to a study from the United States, "IL-7 is integral to the generation and maintenance of CD8(+) T cell memory, and insufficient IL-7 is believed to limit survival and the persistence of memory CD8(+) T cells. Here, we show that during the mouse T cell response to lymphocytic choriomeningitis virus, IL-7 enhanced the number of memory CD8(+) T cells when its administration was restricted to the contraction phase of the response."

"Likewise, IL-7 administration during the contraction phase of the mouse T cell response to...


Source: Vaccine Weekly (2008-04-23)

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