Cancer Vaccines
Hepatitis B virus triggers cell 'suicide' in patients with chronic infection
Published in Vaccine Weekly, April 23rd, 2008
Scientists from UCL (University College London) have identified a key difference between people who can fight the Hepatitis B virus (HBV) off successfully and those who fail to do so – that a group of cells important in controlling the disease are triggered to 'commit suicide' in patients who are chronically infected. This discovery provides an important new focus for developing therapies or vaccines that boost the body's ability to manage this infection.
The researchers analysed thousands of genes in T cells, critical players of the immune system required for control of HBV. They found that T cells from patients who were chronically infected were triggered to 'commit...
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Source: Vaccine Weekly (2008-04-23)
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