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Vaccine Weekly

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HIV/AIDS



Studies in the area of HIV/AIDS reported from University of Zurich



April 23rd, 2008

"The definition of plasma neutralizing antibody titers capable of controlling human immunodeficiency virus (HIV) infection in vivo is considered a critical step in vaccine development. Here we provide estimates for effective neutralization titers by assessing samples from a recent passive immunization trial with the neutralizing monoclonal antibodies (MAbs) 2G12, 2F5, and 4E10 using an analytic strategy that dissects the contributions of these MAbs to the total neutralization activity in patient plasma," researchers in Zurich, Switzerland report.

"Assessment of neutralization activities for six responding patients with partial or complete control of viremia during the...


Source: Vaccine Weekly (2008-04-23)

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