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Bacillus Calmette-Guerin Vaccines
Malaghan Institute of Medical Research publishes research in Bacillus calmette-guerin vaccines
April 23rd, 2008
Data detailed in 'Accelerating the secondary immune response by inactivating CD4(+)CD25(+) T regulatory cells prior to BCG vaccination does not enhance protection against tuberculosis' have been presented. According to recent research from Wellington, New Zealand, "CD4(+)CD25(+) natural T regulatory cells (Tregs) have been shown to suppress protective immune responses in several different vaccination models. Since the effect of Tregs on vaccination against tuberculosis (Tb) was unknown, we used a murine model to investigate whether natural Tregs suppress the development of protective immunity following Mycobacterium bovis bacille Calmette-Guérin (BCG) vaccination."...
Source: Vaccine Weekly (2008-04-23)
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