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Immunization
Research data from S.K. Verma and colleagues update understanding of immunization
April 23rd, 2008
According to a study from Lucknow, India, "Global efforts have been made towards development of vaccine for prevention of lymphatic filariasis. However, lack of thorough knowledge about developmental biology and pathogenesis of filarial parasite restricts us from developing an effective vaccine." "A limited number of immunodominant antigens of human lymphatic filariid Brugia malayi have been characterised; however, none of these recombinant antigens so far induced significant degree of protective immunity to challenge infection. In the present study, we identified a similar to 2.0 Kb cDNA clone by immunoscreening of cDNA library of adult female Brugia malayi. The...
Source: Vaccine Weekly (2008-04-23)
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