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Cancer Vaccines Immunology
Data on cancer vaccines immunology detailed by researchers at University of Regensburg, Department of Hematology-Oncology
April 23rd, 2008
New research, 'Tumor-induced modulation of dendritic cell function,' is the subject of a report. According to recent research from Regensburg, Germany, "Dendritic cells (DC) are specialized antigen presenting cells that acquire, process, and present tumor-associated antigens to T cells for the induction of antigen-specific tumor immune responses. DC have been shown to infiltrate many tumors but both, circulating and tumor-infiltrating DC from cancer patients, appear to be phenotypically and functionally defective." "Several tumor-derived factors such as VEGF, IL-6, IL-10, M-CSF, and STAT-3 have been shown to be responsible for systemic and local DC defects. Furthermore,...
Source: Vaccine Weekly (2008-04-23)
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