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HIV/AIDS Immunology
Scientists at National Institutes of Health target HIV/AIDS immunology
April 23rd, 2008
Scientists discuss in 'Analysis of the human immunodeficiency virus type 1 gp41 membrane proximal external region arrayed on hepatitis B surface antigen particles' new findings in HIV/AIDS. According to a study from the United States, "Vaccine immunogens derived from the envelope glycoproteins of the human immunodeficiency virus type 1 (HIV-1) that elicit broad neutralizing antibodies remain an elusive goal. The highly conserved 30 amino-acid membrane proximal external region (MPER) of HIV gp41 contains the hydrophobic epitopes for two rare HIV-1 broad cross-reactive neutralizing antibodies, 2F5 and 4E10." "Both these antibodies possess relatively hydrophobic HCDR3...
Source: Vaccine Weekly (2008-04-23)
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