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Vaccine Weekly

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Malaria



Reports from I. Nebie and colleagues advance knowledge in malaria



April 30th, 2008

According to a study from Ouagadougou, Burkina Faso, "There is longstanding evidence that immunoglobulin G (IgG) has a role in protection against clinical malaria, and human antibodies of the cytophilic subclasses are thought to be particularly critical in this respect. In this cohort study, 286 Burkinabe children 6 months to 15 years old were kept under malaria surveillance in order to assess the protective role of antibody responses against four antigens which are currently being evaluated as vaccine candidates: apical membrane antigen 1 (AMA1), merozoite surface protein 1-19 (MSP1-19), MSP3, and glutamate-rich protein (GLURP)."

"Total IgG, IgM, and IgG subclass...


Source: Vaccine Weekly (2008-04-30)

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