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Vaccines
Studies from B. Weinberger et al provide new data on vaccines
April 30th, 2008
According to recent research from Rennweg, Austria, "With increasing age, the human immune system undergoes characteristic changes, termed immunosenescence, which lead to increased incidence and severity of infectious diseases and to insufficient protection following vaccination." "Functional defects and altered frequencies of innate and adaptive immune cells impair local responses at the site of vaccine injection, hamper the generation of primary responses to neoantigens, prevent the effective induction of memory lymphocytes, and decrease the effect of booster vaccination. As a result, antibody responses of elderly vaccinees are weaker and decline faster, and long-term...
Source: Vaccine Weekly (2008-04-30)
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