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Vaccine Weekly

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Chickenpox



Studies from B. Watson et al add new findings in the area of chickenpox



April 30th, 2008

"Humoral and cell-mediated immune responses to varicella-zoster virus (VZV) have been evaluated after 1 and 2 doses of live attenuated varicella vaccine, Oka strain, in several studies," scientists in the United States report.

"One dose of varicella vaccine, however, elicits detectable immune responses that are low and, in some cases, may be insufficient for complete protection against the virus after the normal decline in humoral and cell-mediated immunity with time. In contrast, immune responses after 2 doses are significantly higher and approximate the levels seen after natural disease," wrote B. Watson and colleagues.

The researchers concluded:...


Source: Vaccine Weekly (2008-04-30)

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