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Vaccine Weekly

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Flu Vaccines



Studies from X.S. He and co-researchers in the area of flu vaccines published



April 30th, 2008

"The effect of trivalent inactivated influenza vaccine (TIV) or live attenuated influenza vaccine (LAIV) on the phenotypes of circulating influenza-specific CD8(+) T cells was analyzed by interferon (IFN)-gamma flow cytometry and tetramer staining. In adults, the expression of the T cell differentiation marker CD27 on virus-specific CD8(+) T cells decreased after LAIV but increased after TIV," scientists in the United States report.

"In children, expression of the cytotoxicity molecule perforin in influenza-specific CD8(+) T cells increased after TIV but not after LAIV. Among children aged 6 months to 4 years who had not been vaccinated previously and who received 2...


Source: Vaccine Weekly (2008-04-30)

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