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Vaccine Weekly

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Heart Disease



Research from J.P. Werba and co-authors provides new data about heart disease



April 30th, 2008

According to a study from Milan, Italy, "Increased levels of acute phase proteins (APP) in serum are associated with vulnerability of atherosclerotic plaques and acute manifestations of coronary heart disease (CHD). APP have been viewed as indexes of active vascular inflammation or as mediators of atherothrombosis."

"In the present study we tested the hypothesis that individuals who develop stable or unstable forms of CHD might have different innate responses to an inflammatory stimulus. We compared changes in plasma C-reactive protein (CRP) and serum amyloid A (SAA) concentrations 48 h after a standardized inflammatory stimulus (adjuvanted influenza vaccination) in...


Source: Vaccine Weekly (2008-04-30)

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