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HIV/AIDS
Researchers from Technical University of Munich detail findings in HIV/AIDS
April 30th, 2008
According to a study from Munich, Germany, "With HIV persisting lifelong in infected persons, therapeutic vaccination is a novel alternative concept to control virus replication. Even though CD8 and CD4 cell responses to such immunizations have been demonstrated, their effects on virus replication are still unclear." "In view of this fact, we studied the impact of a therapeutic vaccination with HIV nef delivered by a recombinant modified vaccinia Ankara vector on viral diversity. We investigated HIV sequences derived from chronically infected persons before and after therapeutic vaccination. Before immunization the mean +/- SE pairwise variability of patient-derived Nef...
Source: Vaccine Weekly (2008-04-30)
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