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Vaccine Weekly

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Human Papillomavirus



Reports by S.J. Keam and co-researchers describe recent advances in human papillomavirus



April 30th, 2008

"Cervarix (TM) is a prophylactic vaccine comprised of a mixture of virus-like particles derived from the L1 capsid proteins of human papillomavirus (HPV) types 16 and 18 formulated with the AS04 adjuvant system. It is administered by intramuscular injection as a three-dose vaccine regimen at 0, 1 and 6 months," investigators in Auckland, New Zealand report.

"The vaccine is indicated for the prevention of high-grade cervical intraepithelial neoplasia (CIN 2 and CIN 3) and cervical cancer causally related to HPV types 16 and 18. In randomized, double-blind, phase II or III trials in >19 000 women aged 15-25 years, the HPV 16/18 vaccine showed high efficacy in...


Source: Vaccine Weekly (2008-04-30)

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