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Vaccine Weekly

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Rabies Virus



New rabies virus research reported from I.P. Arango and co-authors



April 30th, 2008

According to recent research from Guanajuato, Mexico, "Transgenic plants have been employed successfully as a low-cost system for the production of therapeutically valuable proteins including antibodies, antigens and hormones. Here, we report expression of a full-length nucleoprotein gene of rabies virus in transgenic tomato plants."

"The nucleoprotein was also transiently expressed in Nicotiana benthamiana plants by agroinfiltration. In both cases, the nucleoprotein was expressed at high levels, 1-5% of total soluble protein in tomato and 45% in N. benthamiana. Previously, only epitopes of the nucleoprotein had been expressed in plants. The presence and expression of...


Source: Vaccine Weekly (2008-04-30)

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