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Vaccine Weekly

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Smallpox Vaccines



Research from Emory University broadens understanding of smallpox vaccines



April 30th, 2008

"Ten ischemic cardiac events (ICEs) were reported among 37,901 initial US Department of Health and Human Services (DHHS) smallpox vaccinees. Symptoms developed a median of 10 days after vaccination (range, 028 days)," scientists writing in the journal Clinical Infectious Diseases report.

"The median age of case patients was 56 years (range, 42-65 years), and 60% were mate. Seven (70%) of the case patients had >= 3 cardiac risk factors or probable coronary artery disease before vaccination. Two women, 55 and 57 years of age, experienced acute myocardial infarction and fatal cardiac arrests. Background rates of ICEs during a 3-week period for civilian...


Source: Vaccine Weekly (2008-04-30)

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