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Vaccine Weekly

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Smallpox Vaccines



Study results from I.R. Ortegasanchez and colleagues update understanding of smallpox vaccines



April 30th, 2008

According to recent research published in the journal Clinical Infectious Diseases, "Of>39,000 civilian public health responders vaccinated against smallpox in 2003, 203 reported cardiovascular adverse events (CAEs). An association exists between the US vaccinia strain and myocarditis and/or pericarditis (''myo/pericarditis'' [MP])."

"Other associations are inconclusive. We used surveillance and follow-up survey data of CAE case patients to estimate the resources used during the 2003 smallpox vaccination program and used a probabilistic model to estimate the potential costs of CAEs in a mass vaccination campaign. For every million adult vaccinees, 3001 CAEs...


Source: Vaccine Weekly (2008-04-30)

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