HIV/AIDS Vaccines
Research reports from Case Western Reserve University, Department of Medicine provide new insights into HIV/AIDS vaccines
Published in Vaccine Weekly, April 30th, 2008
Data detailed in 'Assessment of antibody responses against gp41 in HIV-1-infected patients using soluble gp41 fusion proteins and peptides derived from M group consensus envelope' have been presented. According to a study from the United States, "Human immunodeficiency virus type 1 (HIV-1) transmembrane glycoprotein gp41 is targeted by broadly-reactive neutralizing antibodies 2F5 and 4E10, making it an attractive target for vaccine development. To better assess immunogenic properties of gp41, we generated five soluble glutathione S-transferase fusion proteins encompassing C-terminal 30, 64, 100, 142, or 172 (full-length) amino acids of gp41 ectodomain from M group consensus envelope...
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Source: Vaccine Weekly (2008-04-30)
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