Whooping Cough Vaccines
New whooping cough vaccines findings from I.P. Nascimento and co-researchers published
Published in Vaccine Weekly, April 30th, 2008
A report, 'Neonatal immunization with a single dose of recombinant BCG expressing subunit S1 from pertussis toxin induces complete protection against Bordetella pertussis intracerebral challenge,' is newly published data in Microbes and Infection. "The currently used pertussis vaccines are highly efficacious; however, neonates are susceptible to whooping cough up to the sixth month," investigators in Sao Paulo, Brazil report.
"In agreement, DTP-immunized neonate mice were not protected against intracerebral challenge with Bordetella pertussis. Neonate mice immunized with either DTP or a recombinant-BCG strain expressing the genetically detoxified S1...
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Source: Vaccine Weekly (2008-04-30)
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