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Life Sciences
Research from University of Pittsburgh, Department of Surgery provide new insights into life sciences
May 7th, 2008
Researchers detail in 'Memory CD8+ T cells protect dendritic cells from CTL killing,' new data in life sciences. According to a study from the United States, "CD8(+) T cells have been shown to be capable of either suppressing or promoting immune responses. To reconcile these contrasting regulatory functions, we compared the ability of human effector and memory CD8(+) T cells to regulate survival and functions of dendritic cells (DC)." "We report that, in sharp contrast to the effector cells (CTLs) that kill DCs in a granzyme B-and perforin-dependent mechanism, memory CD8(+) T cells enhance the ability of DCs to produce IL-12 and to induce functional Th1 and CTL...
Source: Vaccine Weekly (2008-05-07)
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