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Vaccines
Research from University of California, Los Angeles Biomedical Research Institute provides new data about vaccines
May 7th, 2008
A new study, 'Antibody titer threshold predicts anti-candidal vaccine efficacy even though the mechanism of protection is induction of cell-mediated immunity,' is now available. According to a study from the United States, "We previously reported that vaccination with Freund's adjuvant plus the recombinant N-terminus of the candidal adhesin, Als3p (rAls3p-N), protects mice from disseminated candidiasis. Here we report that the rAls3p-N vaccine is effective when combined with aluminum hydroxide adjuvant." "Antibody titers of >or=1:6400 accurately predicted protection from infection. Nevertheless, neither B lymphocytes nor serum from immunized animals transferred...
Source: Vaccine Weekly (2008-05-07)
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