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Malaria
Research data from I.P. Ceravolo and colleagues update understanding of malaria
May 7th, 2008
"The function of the Plasmodium vivax Duffy binding protein (DBP) during the erythrocyte invasion process is critical for successful parasite growth and pathogenesis in human infections. Although DBP is the subject of intensive malaria vaccine research, investigations on the functional proprieties of anti-DBP antibodies in the human population have been limited [Infect Immun68 (2000) 3164]," investigators in Belo Horizonte, Brazil report. "In the present study, we examined the ability of sera from different populations of the Brazilian Amazon - an area of markedly unstable malaria transmission - to inhibit the erythrocyte-binding function of the DBP ligand domain...
Source: Vaccine Weekly (2008-05-07)
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