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Vaccines
Studies from Seoul National University, Biotechnology Research Institute provide new data on vaccines
May 7th, 2008
Research findings, 'The potential of mannosylated chitosan microspheres to target macrophage mannose receptors in an adjuvant-delivery system for intranasal immunization,' are discussed in a new report. "A vaccine delivery system based on mannosylated chitosan microspheres (MCMs) was studied in vitro and in vivo. Bordetella bronchiseptica antigens containing dermonecrotoxin (BBD) were loaded in MCMs or chitosan microspheres (CMs). Fluorescence confocal microscopy indicated that BBD-loaded MCMs (BBD-MCMs) bound with mannose receptors on murine macrophages (RAW264.7 cells)," scientists in Seoul, Korea report. "In vitro experiments using macrophages demonstrated...
Source: Vaccine Weekly (2008-05-07)
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