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Vaccine Efficacy
Studies from Case Western Reserve University, Medical Department in the area of vaccine efficacy described
May 14th, 2008
According to a study from the United States, "Researchers must often make assumptions about the efficacy of an intervention in a target population without the benefit of trial data specific to that population. Such assumptions may be particularly tenuous with models of vaccination strategies, since the distribution of pathogen strains in target populations may differ substantially from the strain distributions in trial sites." "We describe a technique for projecting expected vaccine efficacy in settings where applying unadjusted trial-based efficacy data may overestimate the benefits of immunization. This simple method uses data describing setting-specific strain...
Source: Vaccine Weekly (2008-05-14)
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