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Vaccine Weekly

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Immunization



Scientists at Banaras Hindu University, Department of Biochemistry publish research in immunization



May 14th, 2008

Current study results from the report, 'Purification and characterization of a leucine aminopeptidase from the bovine filarial parasite Setaria cervi,' have been published. "Using synthetic peptide substrate Leu-p-NA, leucine aminopeptidase (LAP) activity was detected in both microfilarial and adult stages of a bovine filarial parasite Setaria cervi. A single protein fraction containing LAP activity was purified from the adult female S. cervi using three different chromatographic techniques," investigators in Varanasi, India report.

"This purified enzyme was shown to be a 321 kDa zinc dependent metalloexopeptidase having maximum activity at pH 9.0 and 37 degrees C. Its...


Source: Vaccine Weekly (2008-05-14)

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