Vaccine Weekly
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Life Sciences
Reports summarize life sciences research from George Washington University
May 14th, 2008
A new study, 'Necator americanus: the Na-ASP-2 protein secreted by the infective larvae induces neutrophil recruitment in vivo and in vitro,' is now available. According to recent research from the United States, "The L3-secreted Ancylostoma Secreted Protein-2 from the human hookworm Necator americanus (Na-ASP-2) has been selected as a candidate vaccine antigen in anticipation of clinical trials. Its crystal structure revealed that Na-ASP-2 has structural and charge similarities to CC-chemokines, suggesting that it might act as a chemokine mimic when released by the infective larvae during tissue migration." "Using the air pouch model of acute inflammation, we found...
Source: Vaccine Weekly (2008-05-14)
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