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Vaccines
Studies conducted at University of Massachusetts, Department of Medicine on vaccines recently published
May 14th, 2008
Fresh data on vaccines are presented in the report 'Relative immunogenicity and protection potential of candidate Yersinia Pestis antigens against lethal mucosal plague challenge in Balb/C mice.' "Yersinia Pestis outer proteins, plasminogen activator protease and Yop secretion protein F are necessary for the full virulence of Yesinia pestis and have been proposed as potential protective antigens for vaccines against plague. In the current study, we used DNA immunization as a tool to study the relative protective immunity of these proteins with a standardized intranasal challenge system in mice," researchers in the United States report. "While the natural full-length...
Source: Vaccine Weekly (2008-05-14)
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