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HIV/AIDS
Researchers from University of Paris report on findings in HIV/AIDS
May 14th, 2008
"We previously showed that a gp41 peptide (3S) induces expression of a natural killer (NK) ligand (NKp44L) on CD4(+) T cells during HIV-1 infection and that those cells are highly sensitive to NK lysis. In HIV-infected patients, anti-3S antibodies are associated with the maintenance of CD4(+) T cell counts close to their baseline values, and CD4(+) T cells decrease with the antibody titer," scientists in Paris, France report. "This study sought to determine whether anti-3S immunization could prevent NKp44L expression on these CD4(+) T cells in vivo and inhibits the subsequent decline in CD4(+) T cell counts by immunizing macaques with 3S and then infecting them with...
Source: Vaccine Weekly (2008-05-14)
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