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HIV/AIDS
Study results from Massachusetts General Hospital update understanding of HIV/AIDS
May 14th, 2008
In this recent report, researchers in the United States conducted a study "To evaluate the recognition of computationally designed, centralized HIV-1 antigens derived from clade B, C and group M sequences by individuals infected with HIV-1 -M clades B and C. Three centralized sequences have been described - consensus, ancestor and center-of-tree - each of which attempts to minimize the genetic distance to circulating viruses. It is unclear whether any of these sequences affords an advantage for T cell recognition." "The ability of centralized clade B and C and group M peptides to be targeted in ELISpot assays was assessed using samples from the United States, Peru,...
Source: Vaccine Weekly (2008-05-14)
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