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Measles
Research conducted at Mayo Clinic has provided new information about measles
May 14th, 2008
"Toll-like receptors (TLRs) represent the critical ''bridge'' between innate and adaptive immunity to viral pathogens. We hypothesized that single nucleotide potymorphisms (SNPs) that potentially influence the expression/function of TLRs and their associated intracellular signaling molecules contribute to variations in humoral and cellular immunity to measles vaccine," scientists writing in the journal Vaccine report. "We genotyped 190 randomly selected subjects (12-18 years old), previously vaccinated with two doses of measles, for known SNPs in TLR 2, 3, 4, 5, 6, 7, 8 and 9, and their associated intracellular signaling genes. Specific SNPs in the TLR 2, 3, 4,...
Source: Vaccine Weekly (2008-05-14)
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