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Vaccine Weekly

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Cancer Vaccines



Data on cancer vaccines reported by researchers at University of Virginia, Division of Surgical Oncology



May 14th, 2008

Fresh data on cancer are presented in the report 'A multipeptide vaccine is safe and elicits T-cell responses in participants with advanced stage ovarian cancer.' "Nine participants with epithelial ovarian, fallopian tube, or primary peritoneal carcinoma, who were human leukocyte antigen (HLA)-A1, HLA-A2, or HLA-A3, were eligible to enroll in a phase 1 study designed to assess the safety and immunogenicity of a peptide-based vaccine. Participants received 5 class I major histocompatibility complex-restricted synthetic peptides derived from multiple ovarian cancer-associated proteins plus a class II major histocompatibility complex-restricted synthetic helper peptide derived from tetanus...


Source: Vaccine Weekly (2008-05-14)

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