Vaccine Weekly
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Vaccine Weekly
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Immunization
New immunization study results reported from University of Miami
May 21st, 2008
Data detailed in 'Aging down-regulates the transcription factor E2A, activation-induced cytidine deaminase, and Ig class switch in human B cells' have been presented. "Elderly humans have compromised humoral and cellular immune responses, which lead to reduced protection to infectious agents and to vaccines. Currently, available vaccines suboptimally protect the elderly population," researchers in the United States report. "The capacity to class switch the Ig H chain is critical to the effectiveness of humoral immune responses in mice and humans. We have previously shown in mice that the E2A-encoded transcription factor E47, which regulates many B cell functions, is...
Source: Vaccine Weekly (2008-05-21)
|
