Investigators publish new data in the report 'The efficacy of DNAvaccination is enhanced in mice by targeting the encoded protein to dendritic cells.' "DNA vaccines promote an immune response by providing antigen-encoding DNA to the recipient, but the efficacy of such vaccines needs improving. Many approaches have considerable potential but currently induce relatively weak immune responses despite multiple high doses of DNA vaccine," investigators in the United States report.
"Here, we asked whether targeting vaccineantigens to DCs would increase the immunity and protection that result from DNA vaccines. To determine this, we generated a DNA vaccine encoding a fusion...
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