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Vaccinia Virus
Research on vaccinia virus detailed by scientists at University of Rochester
May 21st, 2008
According to recent research published in the Journal of Virology, "The glycoproteins encoded by the vaccinia virus A34R and B5R genes are involved in intracellular envelope virus formation and are highly conserved among orthopoxviruses. A recombinant virus that has the A34R gene deleted and the B5R gene replaced with a B5R gene fused to the enhanced green fluorescent protein (B5R-GFP) gene was created (vB5RrGFP/Delta A34R) to investigate the role of A34 during virion morphogenesis." "Cells infected with vB5R-GFP/Delta A34R displayed GFP fluorescence throughout the cytoplasm, which differed markedly from that seen in cells infected with a normal...
Source: Vaccine Weekly (2008-05-21)
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