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Vaccine Weekly

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Immunization



New immunization research from Ruhr University outlined



May 21st, 2008

In this recent report, researchers in Bochum, Germany conducted a study "To promote the development of improved tumor vaccination strategies relying on the intratumoral expression of viral fusogenic membrane proteins, we elucidated whether the size of syncytia or the way tumor cells die has an effect on the therapeutic outcome. In two syngeneic subcutaneous murine colon cancer models we assessed the anti-neoplastic effect on vector-treated and contralateral untreated tumors."

"Intratumoral injection of a replication-defective adenovirus encoding respiratory syncytial virus fusion protein (RSV-F) alone (Ad.RSV-F) or together with the attachment glycoprotein RSV-G...


Source: Vaccine Weekly (2008-05-21)

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