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Immunization
Researchers at Zhejiang University target immunization
May 28th, 2008
In this recently published article, scientists in Hangzhou, People's Republic of China conducted a study "To achieve high-level expression and secretion of active VP28 directed by a processing-efficient signal peptide in Bacillus subtilis WB600 and exploit the possibility of obtaining an oral vaccine against white spot syndrome virus (WSSV) using vegetative cells or spores as delivery vehicles. The polymerase chain reaction (PCR)-amplified vp28 gene was inserted into a shuttle expression vector with a novel signal peptide sequence." "After electro-transformation, time-courses for recombinant VP28 (rVP28) secretion level in B. subtilis WB600 were analysed. Crayfish were...
Source: Vaccine Weekly (2008-05-28)
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