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Vaccine Weekly

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Malaria



Findings from S. Haase and co-authors provide new insights into malaria



May 28th, 2008

According to recent research from Hamburg, Germany, "One of the key processes in the pathobiology of the malaria parasite is the invasion and subsequent modification of the human erythrocyte. In this complex process, an unknown number of parasite proteins are involved, some of which are leading vaccine candidates."

"The majority of the proteins that play pivotal roles in invasion are either stored in the apical secretory organelles or located on the surface of the merozoite, the invasive stage of the parasite. Using transcriptional and structural features of these known proteins, we performed a genomewide search that identified 49 hypothetical proteins with a high...


Source: Vaccine Weekly (2008-05-28)

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