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Vaccine Weekly

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Gene Therapy



Studies from Duke University, Department of Pediatrics have provided new data on gene therapy



May 28th, 2008

Current study results from the report, 'Adenovirus vector induced innate immune responses: impact upon efficacy and toxicity in gene therapy and vaccine applications,' have been published. "Extensively characterized, modified, and employed for a variety of purposes, adenovirus (Ad) vectors are generally regarded as having great potential by many applied virologists who wish to manipulate and use viral biology to achieve beneficial clinical outcomes. Despite widespread functional prominence and utility (i.e., Ad-based clinical trials have begun to progress to critical Phase III levels, it has recently become apparent that investigations regarding the innate immune response to Ads may reveal...


Source: Vaccine Weekly (2008-05-28)

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