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Anthrax
Studies from Harvard University, Medical Department update current data on anthrax
May 28th, 2008
According to a study from the United States, "Memory CD8(+) T cells are essential for protective immunity against many intracellular pathogens; therefore, stimulation of this population of cells is an important goal of vaccination. We have previously shown that a detoxified derivative of Bacillus anthracis anthrax lethal toxin (LT) can deliver heterologous CD8(+) T-cell epitopes to the major histocompatibility complex class I processing and presentation pathway of murine host cells and that immunization of mice with these LT-antigen fusion proteins leads to the induction of antigen-specific CD8(+) T cells." "In this report we extend these findings to include a detailed...
Source: Vaccine Weekly (2008-05-28)
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