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Cancer Vaccines
Research by N. Mottet and colleagues in cancer vaccines provides new insights
May 28th, 2008
According to recent research from France, "The hormone-refractory status is defined in a confirmed castrated man (who stopped any antiandrogen 6 wk earlier) by three consecutive prostate-specific antigen (PSA) increases above the nadir, reaching at least more than 50% of the nadir. It is standard of care to continue androgen-deprivation therapy (ADT) at this time." "Two randomized phase 3 trials have demonstrated a survival benefit of 2 mo using a 3-wk docetaxel regimen, with a follow up of more than 50 mo. The decision for an immediate or a symptom-triggered-delayed chemotherapy must be tailored on the basis of prognostic factors such as a high PSA level, a short PSA...
Source: Vaccine Weekly (2008-05-28)
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