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Cancer Vaccines
Research in the area of cancer vaccines reported from Y. Shao and colleagues
May 28th, 2008
" The purpose of this study is to identify single nucleotide polymorphisms (SNPs) in the coding region alleles of the X chromosomal LAGE-1 gene, and investigate the frequency of such SNPs in both cancer patients and healthy controls, and thus determine the potential significance of these SNPs with respect to cancer vaccine therapy. In this study, different mRNAs transcribed from the LAGE-1 gene were identified by RT-PCR from healthy donors and cancer patients samples," researchers in Beijing, People's Republic of China report. " A new LAGE-1 allele containing three coding region SNPs (69A/G, 317C/G, and 397T/G) were identified. The allele is highly expressed as the...
Source: Vaccine Weekly (2008-05-28)
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