Cancer Vaccines

Scientists at University of Illinois, Medical Department target cancer vaccines

Published in Vaccine Weekly, May 28th, 2008

According to recent research published in the journal Cancer Research, "This study describes the application of a unique strategy to identify breast cancer antigens [tumor-associated antigen (TAA)]. In a mouse model, the strategy led to the identification of growth factor receptor-bound protein 10 (Grb10) as a newly identified TAA."

"Grb10 is a signal transduction molecule associated with multiple transmembrane tyrosine kinase receptors. It was discovered by comparing microarrays of cellular breast cancer vaccines highly enriched for cells that induced breast cancer immunity in tumor-bearing mice with nonenriched vaccines. The vaccines were prepared by...

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Source: Vaccine Weekly (2008-05-28)

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